Progressive pulmonary fibrosis is mediated by TGF-β isoform 1 but not TGF-β3
نویسندگان
چکیده
منابع مشابه
TGF-β, Smad3 and the process of progressive fibrosis
Transient adenovirus-mediated gene transfer of active TGF-β1 (transforming growth factor-β1) induces severe and progressive fibrosis in rodent lung without apparent inflammation. Alternatively, transfer of IL-1β (interleukin 1β) induces marked tissue injury and inflammation, which develops into progressive fibrosis, associated with an increase in TGF-β1 concentrations in lung fluid and tissue. ...
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ژورنال
عنوان ژورنال: The International Journal of Biochemistry & Cell Biology
سال: 2008
ISSN: 1357-2725
DOI: 10.1016/j.biocel.2007.08.016